Karamanoglu Mehmetbey University is the single university in Karaman and is founded by state. There are also 5 universities at one hour distance, in Konya city which are Selçuk University, Konya Necmettin Erbakan University, Konya Food and Agricultural University, Konya Technical University and KTO Karatay University.

Karamanoğlu Mehmet Bey University has 11 faculties, 2 graduate schools, 6 vocational schools, 3 institutes and 22 research centers. The number of students at Karamanoğlu Mehmetbey University is 17.305  and the number of academic personel is 738. There are 426 academic staff in the university. Since its establisment 14.103 associate degree,  13.483 Bachelor's degree, 630 Master and 15 Doctorate students have been graduated from Karamanoğlu Mehmetbey University. Karamanoğlu Mehmetbey University meets the needs of engineers and technical staff trained for the Food and Energy  sectors that stand out in the region.

As of the 2020-2021 academic year, there are 261 (230 public, 31 private) schools in Karaman. In addition, 52.391 students receive education in public, private and open education institutions. In Karaman, which has an important place in vocational and technical education, 20  schools and 4.247 students receive vocational training for prominent sectors in Karaman. Food departments were opened especially in vocational high schools.Vocational High Schools, Industrial Vocational High Schools and various high schools that provide qualified workforce to different sectors also contribute to the labor force.

Anatolian High Schools and Private Colleges that are providing education in English can be used for the education of  children of foreign investors.

There are 39 pre-school education institutions, 28 official and 11 private, in Karaman during the 2020-2021 academic year.

Schooling Rates;

In Pre- School Education ; %80,81

Schooling rates according to the school age population is %97,08 in Karaman.

8 non-formal training  centers operate in Karaman.

Karaman province has a literacy rate of % 98,01 in terms of basic education. This ratio is %97,24 in Turkey. The proportion of women in illiterate population is higher than men.

According to the TUIK data, the number of students per teacher in Primary Education is 14; in Middle School 14; in Elementary School 11 in Karaman. In  Turkey the number of students per teacher in Primary Education is 17; in Middle School 15; in Elementary School 11.

In 2019-2020, the net schooling  rates for secondary education are 92.70 % in Karaman.